Charles Sturt University
Charles Sturt University

James Wickham

 James Wickham

B.Sp.Sc (Exercise Science), UNSW, Dip.Ed (Phys.Ed), UNSW, B.Sc (Hons) UW, PhD, UW

In 1992 Dr Wickham received a Bachelor of Sports Science (exercise science) from the University of New South Wales and a Diploma of Education (physical education) in 1993 from the same institution. In 1995 he received a 1st Class Honours Degree from the University of Wollongong and a PhD in 2002 which focussed on the activation patterns of skeletal muscle segments around the shoulder joint.

From 1999 to mid 2008 Dr Wickham worked as an Anatomy Lecturer at La Trobe University in Melbourne. He has been employed at CSU from mid 2008 to the present as a Human Anatomy and Physiology Lecturer.

His current research interest is in the use of mesenchymal stem cell therapy for the treatment of osteoarthritis

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Teaching

Teaching philosophy

Dr Wickham's key objective as a teacher is to encourage students to develop a real interest and enthusiasm in the subject matter and hence to empower students with an intrinsic motivation to learn and gain new knowledge.

Current subjects taught
  • BMS129 - Physiological Sciences 1
  • BMS130 - Physiological Sciences 2

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Research

My current research interest is in the non-surgical management of osteoarthritis using mesenchymal stem cells (MSCs).  I work in collaboration with Melbourne Stem Cell Centre, Magellan Stem Cells and Metro Pain Clinic in Melbourne in conducting clinical trials where these stem cells, which are harvested from human adipose tissue, are used for osteoarthritic joints and degenerative intervertebral discs.  Charles Sturt University has ethical oversight of these trials in which there are six current clinical trials running using both donor derived and autologous stem cells for treatment with my role being to help in the publishing of outcome data from these trials. 

Results thus far for the hundreds of patients receiving treatment has been encouraging with significant decreases in pain and increased functionality of their joints.  We hope that this research will lead to MSC therapy to eventually be the front-line treatment option for osteoarthritis.

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Publications

  • Ryan J, Akhter R, Hassan N, Hilton G, Wickham J & Ibaragi S. (2019). Epidemiology of temporomandibular disorder in the general population: a systemic review. Advances in Dentistry and Oral Health, 10(3): DOI: 10.19080/ADOH.2019.10.555787
  • Akhter R, Murray A, Hassan N & Wickham J. (2019).  Temporomandibular disorder symptoms and their association with anxiety and depression among university students.  Advances in Dentistry and Oral Health, 10(3) 555788, DOI: 10.19080/ADOH.2019.10.555788
  • Freitag J, Wickham J, Shah K & Tenen A. (2019).  Effect of autologous adipose-derived mesenchymal stem cell therapy in the treatment of acromioclavicular joint osteoarthritis.  BMJ Case Reports, Open Access 2019;12:e227865. doi:10.1136/bcr-2018-227865
  • Freitag J, Bates D, Wickham J, Shah K, Huguenin L, Tenen A, Paterson K & Boyd D. (2019).  Adipose-derived mesenchymal stem cell therapy in the treatment of knee osteoarthritis: a randomized controlled trial.  Regenerative Medicine, Open Access, 10.2217/rme-2018-0161
  • Freitag J, Norsworthy C, Wickham J, Shah K & Tenen A. (2019).  High tibial osteotomy in combination with arthroscopic abrasion arthroplasty and autologous adipose-derived mesenchymal stem cell therapy in the treatment of advanced knee osteoarthritis.  BMJ Case Reports, Open Access. 2019; 12:e228003, doi: 10.1136/bcr-2018-228003.
  • MacQuarrie AJ, Robertson C, Micalos P, Crane J, High R, Drinkwater E & Wickham JB. (2018). Fit for duty: the health status of New South Wales paramedics.  Irish Journal of Paramedicine, 3(2) DOI.org/10.32378/ijp.v3i2.109
  • Freitag J, Li D, Wickham JB & Shah K. (2017).  The effect of autologous adipose derived mesenchymal stem cell therapy in the treatment of a post-traumatic chondral defect of the knee. BMJ Case Reports. 2017 Oct 15; 2017: bcr-2017.
  • Freitag J, Shah K, Wickham JB, Boyd R & Tenen A. (2017).  The effect of autologous adipose derived mesenchymal stem cell therapy in the treatment of a large osteochondral defect of the knee following unsuccessful surgical intervention of osteochondritis dissecans – a case study. BMC Musculoskeletal Disorders, 18(1):298.  DOI 10.1186/s 12891-017-1658-2.
  • Wickham JB, Mullen NJ, Whyte DG & Cannon J. (2017).  Comparison of energy expenditure and heart rate responses between three commercial group fitness classes. Journal of Science and Medicine in Sport, 20 pp 667-671
  • Tiedemann, A., Rissel, C., Howard, K., Tong, A., Merom, D., Smith, S., Wickham, J.B., Baumann, A., Lord, S.R., Vogler, C., Lindley, R.I., Simpson, J.M., Allman-Farinelli, M. & Sherrington, C. (2016). Health coaching and pedometers to enhance physical activity and prevent falls in community-dwelling people aged 60 years and over: study protocol for the Coaching for Healthy AGEing (CHAnGE) cluster randomised controlled trial.  BMJ Open, 6, e012277.  doi:10.1136/bmjopen-2016-012277
  • Wickham, J.B., Pizzari, T., Balster, S., Ganderton, C. & Watson, L. (2014).  The variable roles of the upper and lower subscapularis during shoulder motion.  Clinical Biomechanics, 29, (8) pp 885-891
  • Pizzari, T., Wickham, J.B., Balster, S., Ganderton, C. & Watson, L. (2014).  Modifying a shrug exercise can facilitate the upward rotator muscles of the scapula.  Clinical Biomechanics, 29, pp 201-205.
  • Stewart, C.J. Whyte, D.G. Cannon, J. Wickham, J.B. & Marino, F. (2013). Exercise-induced dehydration does not alter time trial or neuromuscular performance, International Journal of Sports Medicine, 35, (9) pp 725-730
  • Wickham, J.B. & Brown, J.M.M. (2012). The function of neuromuscular compartments in human shoulder muscles, Journal of Neurophysiology, 107, pp 336-345
  • Scott, L.A. Murley, G.S. & Wickham, J.B. (2012). The influence of footwear on the electromyographic activity of selected lower limb muscles during walking, Journal of Electromyography and Kinesiology, 22, pp 1010-1016
  • Wickham, JB., Pizzari, T., Stansfeld, K., Burnside, A & Watson, L. (2009). Quantifying 'normal' shoulder muscle activity during abduction. Journal of Electromyography and Kinesiology, 20 [Epub ahead of print].
  • Murley, G.S., Buldt, A.K., Trump, P.J. & Wickham, J.B. (2009). Tibialis posterior EMG activity during barefoot walking in people with neutral foot posture. Journal of Electromyography and Kinesiology, 19 pp e69-e77.
  • Brown, J.M.M., Wickham, J.B., McAndrew, D.J. & Huang, X-F. (2007). Muscles within muscles: Coordination of 19 muscle segments within three shoulder muscles during isometric motor tasks, Journal of Electromyography and Kinesiology, 17 (1) pp 57-73.
  • Brown, J.M.M. & Wickham, J.B. (2006). Neuromotor coordination of multisegmental muscle during a change in movement direction. Journal of Musculoskeletal Research, 10, (2) pp 63-74
  • Buldt, A., Trump, P., Murley, G & Wickham, J.B. Electromyographic activity
    of tibialis posterior in neutral foot types during barefoot walking. (2007). Clinical Anatomy, 20: p 573.
  • Wickham, J.B., Brown, J.M.M., McAndrew, J.M., & Green,R. (2004). Muscles within muscles:The classical triphasic EMG burst and its applicability to segments of large radiate agonist/antagonistic muscles, Journal of Musculoskeletal Research, 8, Nos 2 & 3, pp107-117.
  • Wickham, J.B., Brown, J.M.M. & McAndrew, J.M. (2004). Muscles within muscles: anatomical and functional segmentation of selected shoulder joint musculature, Journal of Musculoskeletal Research, 8 (1) pp 57-73.
  • Dowling, A., Downey,B.,Green,R., Wickham,J., & Reddy, P. (2003) Anatomical and possible clinical relationships between the calcaneofibular ligament and peroneus brevis-a pilot study. Manual Therapy, 8 (3), pp 170-175.
  • Wickham, J.B. (2002) Muscles within muscles: the neuromotor activation patterns of intramuscular segments, PhD Thesis, University of Wollongong.
  • Wickham, J.B. and Brown, J.M.M. (1998). Muscles within muscles: the neuromotor control of intramuscular segments. European Journal of Applied Physiology, 78, pp 219-225.

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